856: Trimer Interface Redesign: Round 3

Closed since about 12 years ago

Summary

• Created: March 07, 2014
• Expires: March 10, 2014 at 23:00 UTC
• Max points: 100

Description

This is the third round in a series of interface redesign puzzles with increasing tolerance for buried blue, polar residues. Try to redesign a more polar interface between the symmetric subunits of this protein! This symmetric trimer was originally designed by Museka in Puzzle 742. See Puzzle 851 for more information. Due to some bugs apparent in previous rounds of this puzzle, players will NOT be able to load in solutions from Puzzles 851 or 852.

Top groups

• 1. Anthropic Dreams 100 pts. 15,040
• 2. Beta Folders 82 pts. 14,916
• 3. Void Crushers 66 pts. 14,865
• 4. Contenders 53 pts. 14,720
• 5. Russian team 42 pts. 14,697
• 6. L'Alliance Francophone 33 pts. 14,687
• 7. HMT heritage 26 pts. 14,608
• 8. Go Science 20 pts. 14,556
• 9. Deleted group pts. 14,528
• 10. Italiani Al Lavoro 11 pts. 14,463

Top soloists

• 1. karstenw 100 pts. 15,040
• 2. matosfran 98 pts. 14,916
• 3. bertro 95 pts. 14,891
• 4. caglar 93 pts. 14,884
• 5. hansvandenhof 90 pts. 14,881
• 6. Timo van der Laan 88 pts. 14,865
• 7. Galaxie 86 pts. 14,757
• 8. g_b 83 pts. 14,718
• 9. gmn 81 pts. 14,698
• 10. auntdeen 79 pts. 14,688

Comments

[wisky]

There's a score term (represented by the 'Hiding' subscore) in these puzzles that inflicts a penalty when a polar residue is in close proximity to many other residues (i.e. in the core of the protein).

This relative weight of this score term is reduced in each iteration of the puzzle.

[bkoep]

There's a score term (represented by the 'Hiding' subscore) in these puzzles that inflicts a penalty when a polar residue is in close proximity to many other residues (i.e. in the core of the protein).

This relative weight of this score term is reduced in each iteration of the puzzle.

[wisky]

Thanks for the response, bkoep :D