Foldit Puzzles
Play puzzles to help scientific research and compete with other players. New puzzles are posted every week.
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Our next Mini-CASP target, whose structure will be released very soon, has close homologs that we can use as templates. There are 3 different templates you can choose from by clicking 'Show Alignment' from the actions tab. NOTE: We might have to close this puzzle early if the native is released before friday. For players with fewer than 150 global points.
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Our next Mini-CASP target, whose structure will be released very soon, has close homologs that we can use as templates. There are 3 different templates you can choose from by clicking 'Show Alignment' from the actions tab. NOTE: We might have to close this puzzle early if the native is released before friday.
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This is a puzzle for beginners who have recently finished the tutorial levels. Play around, try out tools, and practice your folding instinct. See if you can get close to the guide.
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This is a puzzle for beginners who have recently finished the tutorial levels. Play around, try out tools, and practice your folding instinct. See if you can get close to the guide.
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Our next Quest to the Native is based on Mini-CASP 8, but starting from an extended chain. This might be more difficult than usual, but we would like to see if you are able to reach this recently released native structure when given a guide of it, with a freestyle starting structure. Only the buried sidechains will be shown on the native guide.
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Our next Quest to the Native is based on Mini-CASP 8, but starting from an extended chain. This might be more difficult than usual, but we would like to see if you are able to reach this recently released native structure when given a guide of it, with a freestyle starting structure. Only the buried sidechains will be shown on the native guide. For players with fewer than 15 global points.
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Our next Quest to the Native is based on Mini-CASP 8, but starting from an extended chain. This might be more difficult than usual, but we would like to see if you are able to reach this recently released native structure when given a guide of it, with a freestyle starting structure. Only the buried sidechains will be shown on the native guide. For players with fewer than 150 global points.
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This is the first sequence alignment puzzle! You can choose "Show Alignment" from the Actions tab to use the new sequence alignment tool. See if you can find a better alignment than the starting one for this structure!
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More protein and DNA puzzles! Again, there are several mutatable segments on the protein near the DNA. Try to get a better score!
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Our next Quest to the Native is based on Mini-CASP 3, but starting from an extended chain. This might be more difficult than usual, but we would like to see if you are able to reach this recently released native structure when given a guide of it, with a freestyle starting structure. Only the buried sidechains will be shown on the native guide.
