Foldit Puzzles
Play puzzles to help scientific research and compete with other players. New puzzles are posted every week.
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To practice for CASP, here is the first VOTING puzzle where we ask you to vote for the structures you believe are the best. Use the public solution widget to look at all 5 solutions, then click on the button to go to the webpage and vote! You can also vote directly at http://fold.it/portal/node/987472. See the blogpost for more details.
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Since puzzle 271 is proving to be tough (Difficulty level: Advanced, indeed!) here are more templates for Mini-CASP 17 before we post some Rosetta@home predictions.
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Since puzzle 271 is proving to be tough (Difficulty level: Advanced, indeed!) here are more templates for Mini-CASP 17 before we post some Rosetta@home predictions. For players with fewer than 15 global points.
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Since puzzle 271 is proving to be tough (Difficulty level: Advanced, indeed!) here are more templates for Mini-CASP 17 before we post some Rosetta@home predictions. For players with fewer than 150 global points.
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Excellent work on the previous Hold it! puzzle! After austinday analyzed your solutions, we've made a few changes to the setup for this new round. In particular you should try to: 1) avoid mutations to Arginine, Lysine, Aspartate, and Glutamate. 2) make at most three hydrogen bonds at the very tip of the ligand. 3) make even more ideal hydrogen bonds. When they are unideal, you'll notice the unideal angles will appear as red lines. The green line near them shows a more ideal angle! We're starting you off with some interesting designs that came out of the previous round so you don't have to start from scratch. Again, we don't know if it's possible!
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The native solved structure for Mini-CASP 16 was just released, so we are giving you the same exact puzzle as 265: Mini-CASP 16 - Quick Alignment, but this time with the native shown as a guide. We hope this will help you with the new alignment tool! Only the buried sidechains will be shown on the native guide.
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The native solved structure for Mini-CASP 16 was just released, so we are giving you the same exact puzzle as 265: Mini-CASP 16 - Quick Alignment, but this time with the native shown as a guide. We hope this will help you with the new alignment tool! Only the buried sidechains will be shown on the native guide. For players with fewer than 15 global points.
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The native solved structure for Mini-CASP 16 was just released, so we are giving you the same exact puzzle as 265: Mini-CASP 16 - Quick Alignment, but this time with the native shown as a guide. We hope this will help you with the new alignment tool! Only the buried sidechains will be shown on the native guide. For players with fewer than 150 global points.
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Here is the next Mini-CASP target whose solved structure will be released soon. Mini-CASP 17 has close homologs that we can use as templates. There are 3 different templates you can choose from by clicking 'Show Alignment' from the actions tab. We will give you Rosetta@home predictions for this target next week.
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Here is the next Mini-CASP target whose solved structure will be released soon. Mini-CASP 17 has close homologs that we can use as templates. There are 3 different templates you can choose from by clicking 'Show Alignment' from the actions tab. We will give you Rosetta@home predictions for this target next week. For players with fewer than 15 global points.