Foldit Puzzles
Play puzzles to help scientific research and compete with other players. New puzzles are posted every week.
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This is the last chance to improve the solutions to Mini-CASP 11 before the native is released in a few days. Here are the predictions from the top 5 scoring groups for Mini-CASP 11 puzzle 229. It might be hard to improve the Foldit scores on these 5 models (since these were top-scoring Foldit predictions) but hopefully seeing another player's solution might lead you to a winning prediction! Each time you reset the puzzle one of these 5 Foldit predictions will be randomly chosen. We hope you can try them all out before they expire this friday. For players with fewer than 15 global points.
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This is the last chance to improve the solutions to Mini-CASP 11 before the native is released in a few days. Here are the predictions from the top 5 scoring groups for Mini-CASP 11 puzzle 229. It might be hard to improve the Foldit scores on these 5 models (since these were top-scoring Foldit predictions) but hopefully seeing another player's solution might lead you to a winning prediction! Each time you reset the puzzle one of these 5 Foldit predictions will be randomly chosen. We hope you can try them all out before they expire this friday. For players with fewer than 150 global points.
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This is a Rosetta@home prediction for the even more difficult de-novo Mini-CASP 10 target. We hope that you can improve this Rosetta model. Good luck!
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This is a Rosetta@home prediction for the even more difficult de-novo Mini-CASP 10 target. We hope that you can improve this Rosetta model. Good luck! For players with fewer than 15 global points.
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This is a Rosetta@home prediction for the even more difficult de-novo Mini-CASP 10 target. We hope that you can improve this Rosetta model. Good luck! For players with fewer than 150 global points.
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This is a Rosetta@home prediction for the difficult de-novo Mini-CASP 11 target. We hope that you can improve this Rosetta model.
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This is a Rosetta@home prediction for the difficult de-novo Mini-CASP 11 target. We hope that you can improve this Rosetta model. For players with fewer than 15 global points.
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This is a Rosetta@home prediction for the difficult de-novo Mini-CASP 11 target. We hope that you can improve this Rosetta model. For players with fewer than 150 global points.
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In this puzzle you can change a different region to fill the holes near the ligand! Check out the blog for more information!
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Our 10th Mini-CASP target is another de-novo (or ab-initio) target. This means that there is no solved structure that has a similar sequence that we can start our predictions from. This is exciting because template-free targets are rare (in CASP8 only 11 of the 128 targets were free-modeling targets) so we are lucky to be able to predict this. Since we have no idea where to even start, we are giving you an extended chain to see what you come up with. This might not be easy, so we will give you Rosetta@home predictions for this target as puzzles next week. Until then, good luck freestyle folding! The secondary structure prediction is posted in the puzzle comments.