Foldit Puzzles
Play puzzles to help scientific research and compete with other players. New puzzles are posted every week.
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For this 110 residue CASP11 Target, T0824, we are starting you off with 3 different server predictions selected by our WeFold collaborators. Resetting the puzzle will cycle through each model and they are available in the Alignment Tool so you can use partial threading between them. Secondary structure predictions are in the puzzle comments.
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For this 115 residue CASP11 Target, T0822, we are giving you 3 different server predictions selected by our WeFold collaborators. Resetting the puzzle will cycle through each model and they are available in the Alignment Tool so you can use partial threading between them. Secondary structure predictions are in the puzzle comments.
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For this 140 residue CASP11 Target, T0820, we are giving you 5 different server predictions selected by our WeFold collaborators. Resetting the puzzle will cycle through each model and they are available in the Alignment Tool so you can use partial threading between them. Secondary structure predictions are in the puzzle comments.
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This CASP refinement target has 80 residues. We've been told that ~58% of this starting structure is correct. High Wiggle Power has been enabled for this puzzle.
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For this 143 residue CASP11 Target, T0818, we are giving you 4 different server predictions selected by our WeFold collaborators. Resetting the puzzle will cycle through each model and they are available in the Alignment Tool so you can use partial threading between them. Secondary structure predictions are in the puzzle comments.
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For this 68 residue CASP11 Target, T0816, we are starting you off with 4 different server predictions selected by our WeFold collaborators. Resetting the puzzle will cycle through each model. Please try out each server start. Although one server model scores better than the rest initially, it might be the furthest from the native and might not get you the most points in the end! Secondary structure predictions are in the puzzle comments.
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For this target, the CASP11 organizers have provided additional "correct" contact predictions, which we have combined with the sparse data contacts from Puzzle 920b. Contacts are scored with the Contact Map filter in this puzzle, and there is an upper limit of 985 possible points from the filter. Players will NOT be able to load in solutions from previous puzzles. See the puzzle comments for secondary structure predictions!
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This CASP refinement target has 155 residues. We've been told that ~39% of this starting structure is correct. High Wiggle Power has been enabled for this puzzle.
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This CASP refinement target has 168 residues. We've been told that ~41% of this starting structure is correct. High Wiggle Power has been enabled for this puzzle.
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For this target, the CASP11 organizers have provided "sparse" experimental data about possible contacts in the protein. Contacts are factored directly into your score in this puzzle, and contribute to the "Backbone" subscore. The starting structure is an extended chain, and secondary structure predictions can be found below in the puzzle comments.