Foldit Puzzles

413: De-novo Freestyle 6

We are giving it to you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well. Since this protein chain is quite long, we are giving you 3 extra days to work on it.

414: New Style Exploration Puzzle Round 1

A new style of exploration puzzle. Increase your score multiplier by exploring new structures. Exploring further will give you a higher multiplier. Use the Contact Map to figure out where to explore. To start, go to [Actions] -> [Contact Map].

412: Electron Density Trace Puzzle

This Rosetta model was generated by trying to fit an electron density map, but as you can see the resulting trace looks pretty bad. We have tried various Rosetta protocols on this model but they aren't able to make it look any better, so we are hoping your human skills can spot what areas need to be improved the most.

412 (<15): Electron Density Trace Puzzle

This Rosetta model was generated by trying to fit an electron density map, but as you can see the resulting trace looks pretty bad. We have tried various Rosetta protocols on this model but they aren't able to make it look any better, so we are hoping your human skills can spot what areas need to be improved the most. For players with fewer than 15 global points.

412 (<150): Electron Density Trace Puzzle

This Rosetta model was generated by trying to fit an electron density map, but as you can see the resulting trace looks pretty bad. We have tried various Rosetta protocols on this model but they aren't able to make it look any better, so we are hoping your human skills can spot what areas need to be improved the most. For players with fewer than 150 global points.

Beginner Puzzle: T-cell Lymphoma Invasion Protein

This is a Beginner puzzle for new players that have recently completed the Intro Puzzles. The starting model is very far from the correct native structure, can you use the Foldit tools you just learned to fix the model and match the guide?

Beginner Puzzle (<15): T-cell Lymphoma Invasion Protein

This is a Beginner puzzle for new players that have recently completed the Intro Puzzles. The starting model is very far from the correct native structure, can you use the Foldit tools you just learned to fix the model and match the guide? For players with fewer than 15 global points.

Beginner Puzzle (<150): T-cell Lymphoma Invasion Protein

This is a Beginner puzzle for new players that have recently completed the Intro Puzzles. The starting model is very far from the correct native structure, can you use the Foldit tools you just learned to fix the model and match the guide? For players with fewer than 150 global points.

411: Five Templates Alignment Tool Puzzle

This currently unsolved protein has homologs that we can use as templates. There are 5 templates you can thread from in the Alignment Tool. Make sure to try Intro Puzzles 5-1 to 5-3 if you aren't familiar with the Alignment Tool. Alignment Tool help can be found here: http://foldit.wikia.com/wiki/Alignment_Tool. See hints in the puzzle comments if you are unable to thread.

411 (<15): Five Templates Alignment Tool Puzzle

This currently unsolved protein has homologs that we can use as templates. There are 5 templates you can thread from in the Alignment Tool. Make sure to try Intro Puzzles 5-1 to 5-3 if you aren't familiar with the Alignment Tool. Alignment Tool help can be found here: http://foldit.wikia.com/wiki/Alignment_Tool. See hints in the puzzle comments if you are unable to thread. For players with fewer than 15 global points.