Foldit Puzzles

650: Server models for R0023

As mentioned in Puzzle 645, we are giving you server predictions for this CASP ROLL target. Resetting the puzzle will cycle through 8 different server predictions and they are available in the Alignment Tool so you can use partial threading between them. Please try out each start, as the topology that initially scores poorly may actually be the closest to the native and will eventually score better than everything else

649: Server models for R0022

As mentioned in Puzzle 642 we are giving you server predictions for each CASP ROLL target. Resetting the puzzle will cycle through 8 different server predictions and they are available in the Alignment Tool so you can use partial threading between them. Please try out each start, as the topology that initially scores poorly may actually be the closest to the native and will eventually score better than everything else

647: Electron Density for CASP10 Target T0691

We are very excited about this puzzle, as this is our first BLIND Electron Density puzzle. The native for CASP10 Target T0691 still has not been released, but we are able to give you Electron Density information for it. Unfortunately, because this is experimental data, this is not going to be an easy puzzle. Since this one is going to be particularly tough, we are giving you 2 weeks and it is worth 200 global points! The density in this puzzle is off on the right end of the chain you start with. If you want to move it to the center, try aligning to the density and then pressing Q.

648: Server models for R0021

As mentioned in Puzzle 643, we are giving you server predictions for each CASP ROLL target. Resetting the puzzle will cycle through 10 different server predictions (this target is so tough, they are all different) and they are available in the Alignment Tool so you can use partial threading between them. Please try out each start.

646: Server models for R0020

As mentioned in Puzzle 641, we are giving you server predictions for each CASP ROLL target. Resetting the puzzle will cycle through 7 different server predictions (that are similar to one another) and they are available in the Alignment Tool so you can use partial threading between them. Please try out each start, as the topology that initially scores poorly may actually be the closest to the native and will eventually score better than everything else

645: CASP ROLL Target R0023

Another CASP ROLL target. We are again providing you with 3 very different templates for now, and will give you with some server predictions once they are released. More details about this CASP target are in the puzzle comments.

Beginner Puzzle: Platypus Venom

This is a short 42-residue protein found in duckbilled platypus venom for new players to try out after completing the Introductory Puzzles. The native is shown as a guide on this puzzle, so try using everything you've learned in the Intro levels to match the native fold. The guide can be turned on/off with Shift-S.

644: Photo-Electric Hydrogenase Catalyst 1

This particular puzzle is a test-run involving a potentially very useful hydrogen-producing catalyst, attached to four symmetric chains. For now, we just want to see what sorts of interesting structures you can come up with (see the new blogpost for more details). We’re using the "ResidueIE filter" again to make it tougher to expose hydrophobic residues and bury polar groups.

643: CASP ROLL Target R0021

Here is the next CASP ROLL target. We are again providing you with 3 templates for now, and will give you with some server predictions once they are released. More details about this CASP target are in the puzzle comments.

642: CASP ROLL Target R0022

Another CASP ROLL target. We are again providing you with 3 very different templates for now, and will give you with some server predictions once they are released. More details about this CASP target are in the puzzle comments.