Foldit Puzzles

613: CASP10 Refinement Puzzle: TR655

The twenty-second CASP10 Refinement Target was the best server prediction for target T0655, generated by the Tasser_VMT server. We've been told that ~69% of this model matches the native, so you'll need to significantly change the starting model. Luckily, they have told us which regions to focus on 1-15 & 46-59 (as well as which to ignore: residues 86-88 & 137-158). These regions are shown in Note Mode. More info in the puzzle comments.

610: CASP10 Refinement Puzzle: TR750

This is the twentieth CASP10 Refinement Target. We've been told that ~77% of this model matches the native, so you'll need to refine ~23% of the structure! More info in the puzzle comments.

611: CASP10 Refinement Puzzle: TR752

This is the twenty-first CASP10 Refinement Target. This model was the best server prediction for target T0752, generated by the BAKER-ROSETTASERVER (using Rosetta@home). We've been told that ~90% of this model matches the native! So (for once) you won't need to change the starting model much. In addition, the organizers have given us "Special attention regions: 41-50, 100-110, 125-128." These are highlighted in Note Mode.

612: Quick CASP10 Refinement Puzzle: TR722

As mentioned in Puzzle 608: this Rosetta model was the best server prediction for target T0722, but only ~58% of this model matches the solved structure. We are giving you this model without symmetry, in case it folds up as a monomer. This quick puzzle is worth 70 global points. More info in the puzzle comments.

609: Beginner CASP10 Refinement Puzzle: TR696

This is the nineteenth CASP10 Refinement Target. This model was the best server prediction for target T0696, generated by the Bilab-Enable server. We've been told that ~71% of this model matches the native, so you just need to find which 29% to refine! Luckily, this is a short target with only 100 residues. More info in the puzzle comments.

608: Symmetric CASP10 Refinement Puzzle: TR722

This is the eighteenth CASP10 Refinement Target. This model was the best server prediction for target T0722, generated by the BAKER-ROSETTASERVER (using Rosetta@home). Despite being the prediction closest to the native, almost half of the model is incorrect: only ~58% of this model matches the solved structure. We believe that one possible reason is that this protein folds up as a dimer, so we are giving you the model with symmetry. Please read the puzzle comments for additional details.

606: Large CASP10 Refinement Puzzle: TR708

The sixteenth CASP10 Refinement Target has 196 residues! This model was the best server prediction for target T0708, generated by the MULTICOM server. We've been told that ~86% of this model matches the native, so you just need to find which 14% to refine! We are giving you extra time to work on this one due to its size. More info in the puzzle comments.

607: Beginner CASP10 Refinement Puzzle: TR747

This is the seventeenth CASP10 Refinement Target. This model was the best server prediction for target T0747, generated by the Mufold server. We've been told that ~83% of this model matches the native, so you just need to find which 17% to refine! Luckily, this is a short target with only 98 residues. More info in the puzzle comments.

605: CASP10 Refinement Puzzle: TR710

This is the fifteenth CASP10 Refinement Target. We've been told that about 75% of this model matches the native, so you'll need to refine ~25% of the structure! More info in the puzzle comments.

604: CASP10 Refinement Puzzle: TR698

This is the fourteenth CASP10 Refinement Target. This model was the best server prediction for target T0698, generated by the PMS server. We've been told that ~65% of this model matches the native, so you'll need to significantly change the starting model. Luckily, they have told us which regions require special attention: residues 17-35 & 90-100. These regions are shown in Note Mode. More info in the puzzle comments.