Foldit Puzzles
Play puzzles to help scientific research and compete with other players. New puzzles are posted every week.
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Closed since almost 14 years agoThe seventh CASP10 target is not an easy one, as it's 163 residues and we don't have any alignments for the first 18 residues. We are providing you with 5 different templates, but all of them have a similar topology (that we hope is the correct one!). We will provide you with server predictions once they are released. More details about this CASP target are in the puzzle comments.
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Closed since almost 14 years ago
As mentioned in Puzzle 564, we are giving you some server predictions for this CASP10 target. Resetting the puzzle will cycle through 6 different server predictions and they are available in the Alignment Tool so you can use partial threading between them. Please try to work on each of the 6 server models, not just the one that gets you the most points after a couple days. The other models might get you a better score eventually!
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Closed since almost 14 years ago
As mentioned in Puzzle 561, we are giving you some server predictions for this CASP10 target. Resetting the puzzle will cycle through 6 different server predictions and they are available in the Alignment Tool so you can use partial threading between them. Please try to work on each of the 6 server models, not just the one that gets you the most points after a couple days. The other models might get you a better score eventually!
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Closed since almost 14 years ago
As mentioned in Puzzle 562, we are uncertain of the topology for T0680. We are providing you with 5 templates that span two very different topologies (in addition to the symmetry one in 562) before providing you with the server predictions that will be released next week. Please try out BOTH topologies! More details in the puzzle comments.
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Closed since almost 14 years ago
As mentioned in Puzzle 559, we are giving you some server predictions for this CASP10 target. Resetting the puzzle will cycle through 5 different server predictions and they are available in the Alignment Tool so you can use partial threading between them. Please try to work on each of the 5 server models, not just the one that gets you the most points after a couple days. The other models might get you a better score eventually!
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Closed since almost 14 years ago
As mentioned in Puzzle 558, we are giving you some server predictions for this CASP10 target. Resetting the puzzle will cycle through 6 different server predictions and they are available in the Alignment Tool so you can use partial threading between them. Please try to work on each of the 6 server models, not just the one that gets you the most points after a couple days. The other models might get you a better score eventually!
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Closed since almost 14 years ago
Yet another tough one! None of the alignment programs were able to find good templates for this target, and it might be the case that this protein has no homologs. We are giving you 7 templates (in hope that one of them is correct) for now, and will provide you with some server predictions once they are released. More details about this CASP target are in the puzzle comments.
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Closed since almost 14 years ago
562: Quick Symmetric CASP10 T0680 Puzzle
Closed Beginner Beginner Beginner Beginner Beginner Beginner Beginner Overall Overall Overall Overall Overall Overall Overall Prediction Prediction Prediction Prediction Prediction Prediction Prediction Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry562: Quick Symmetric CASP10 T0680 Puzzle
Closed Beginner Beginner Beginner Beginner Beginner Beginner Beginner Overall Overall Overall Overall Overall Overall Overall Prediction Prediction Prediction Prediction Prediction Prediction Prediction Symmetry Symmetry Symmetry Symmetry Symmetry Symmetry SymmetryThis target is so tough, we aren't even sure of its topology! What we do believe is that one possible topology is a coiled coil (please look at the screenshot of a template in the puzzle comments) so we are giving you this model to fold using symmetry. We will post the other non-symmetric topologies as regular puzzles.
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Closed since almost 14 years ago
This is another tough one! None of the alignment programs were able to find good templates for this target, and it might be the case that this protein has no homologs. Again we are giving you 6 templates (in hope that one of them is correct) for now, and will provide you with some server predictions once they are released. More details about this CASP target are in the puzzle comments.
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Closed since almost 14 years ago
This puzzle is very similar to puzzle 557. Again, most of the server predictions for T0660 were very similar except for the last 50 residues. Getting this C-terminal region right will separate the best predictions from the worst ones for this CASP10 target. Focus on folding the last 50 residues with the rest of the protein. You can use the Alignment Tool to insert a cutpoint between these regions. More info in the puzzle comments.