Foldit Puzzles

445 (<150): CASP9 Refinement Puzzle 8 - Double Start with constraints

This puzzle had an error in it and has been reposted as Puzzle 445b. For players with fewer than 150 global points.

444: De-novo Freestyle 11

We are giving you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.

443: Mini Arabidopsis Multi-Start Puzzle

This small unsolved Arabidopsis protein only has 59 residues and negatively controls the biosynthesis of starch in plants and regulates leaf and seed composition. We are giving you 5 Zhang server models as starts for this puzzle. Each time you reset the puzzle one of them will randomly be chosen. They are also in the Alignment Tool so you can use partial threading and an extended chain. More info in the puzzle comments.

443 (<15): Mini Arabidopsis Multi-Start Puzzle

This small unsolved Arabidopsis protein only has 59 residues and negatively controls the biosynthesis of starch in plants and regulates leaf and seed composition. We are giving you 5 Zhang server models as starts for this puzzle. Each time you reset the puzzle one of them will randomly be chosen. They are also in the Alignment Tool so you can use partial threading and an extended chain. More info in the puzzle comments. For players with fewer than 15 global points.

443 (<150): Mini Arabidopsis Multi-Start Puzzle

This small unsolved Arabidopsis protein only has 59 residues and negatively controls the biosynthesis of starch in plants and regulates leaf and seed composition. We are giving you 5 Zhang server models as starts for this puzzle. Each time you reset the puzzle one of them will randomly be chosen. They are also in the Alignment Tool so you can use partial threading and an extended chain. More info in the puzzle comments. For players with fewer than 150 global points.

442: Slightly Constrained Exploration Puzzle Round 2

Explore away from the top solutions from round 1 to increase your multiplier. You can use threading to use all or part of any of these solutions, but remember, just copying all of one solution wont get you any points! Try using just part or using a previous solution as a starting point and form new contacts!

441: De-novo Freestyle 10

We are giving you this currently unsolved protein as an extended chain. Use all your skills to fold it up as best as you can. The secondary structure predictions are posted in the puzzle comments, but we have included them in the starting structure as well.

440: CASP9 Refinement Puzzle 8B with constraints

We are reposting puzzle 351: CASP9 Refinement Puzzle 8B, because the native structure still has not been released. This time, however, we would like to see if these few constraints are helpful.

440 (<15): CASP9 Refinement Puzzle 8B with constraints

We are reposting puzzle 351: CASP9 Refinement Puzzle 8B, because the native structure still has not been released. This time, however, we would like to see if these few constraints are helpful. For players with fewer than 15 global points.

440 (<150): CASP9 Refinement Puzzle 8B with constraints

We are reposting puzzle 351: CASP9 Refinement Puzzle 8B, because the native structure still has not been released. This time, however, we would like to see if these few constraints are helpful. For players with fewer than 150 global points.